https://www.arcalyst.com/ 2026-05-18 https://www.arcalyst.com/sites/arcalyst.com/files/Arcalyst_Logo_REVISED_RGB.png ARCALYST® (rilonacept) for injection Logo. https://www.arcalyst.com/sites/arcalyst.com/files/styles/large/public/2022-12/Arcalyst_Logo_REVISED_KO.png?itok=InMBq9Uw ARCALYST® (rilonacept) for injection Logo. https://www.arcalyst.com/sites/arcalyst.com/files/2022-10/kiniksa-logo.svg Kiniksa Logo. https://www.arcalyst.com/dira 2026-05-18 https://www.arcalyst.com/sites/arcalyst.com/files/styles/large/public/2023-04/thumbnail-arcalyst-bottle.png?itok=E_pBRjSX ARCALYST® (rilonacept) vial. https://www.arcalyst.com/sites/arcalyst.com/files/styles/retina/public/2021-03/subcutaneous_definition_desktop%403x.png?itok=RPizjIQk Self-Administered means you give the injection to yourself + Subcutaneous means under the skin https://www.arcalyst.com/sites/arcalyst.com/files/styles/retina/public/2021-03/subcutaneous_definition_mobile%403x.png?itok=5y4-K_j2 Self-Administered means you give the injection to yourself + Subcutaneous means under the skin https://www.arcalyst.com/sites/arcalyst.com/files/styles/retina/public/2021-02/dosing%402x.png?itok=jm1dbsAg ARCALYST® (rilonacept) first injection at doctor's office. https://www.arcalyst.com/sites/arcalyst.com/files/styles/retina/public/2023-03/thumbnail-how-to-use-arcalyst-guide.png?itok=gOPa-i79 ARCALYST® (rilonacept) Step-by-step instructions for self-administration brochure. https://www.arcalyst.com/sites/arcalyst.com/files/styles/icon/public/2021-02/starting_treatment%402x.png?itok=rEFnb4CZ Starting treatment. https://www.arcalyst.com/sites/default/files/styles/coh_medium/public/images/caps/testimonial-1.jpg Patient Access Lead. https://www.arcalyst.com/sites/default/files/images/caps/icon-pig.jpg Financial assistance. https://www.arcalyst.com/sites/default/files/styles/coh_medium/public/images/caps/testimonial-2.jpg Patient Access Lead. https://www.arcalyst.com/sites/arcalyst.com/files/styles/icon/public/2021-03/KOC_treatment_support%403x.png?itok=hiWN9Fda Treatment support. https://www.arcalyst.com/sites/default/files/styles/coh_medium/public/images/caps/testimonial-3.jpg Patient Access Lead. https://www.arcalyst.com/sites/arcalyst.com/files/styles/icon/public/2021-03/contact_icon%403x.png?itok=roxkKQyk Call Kiniksa OneConnect. https://www.arcalyst.com/caps 2026-05-18 https://www.arcalyst.com/sites/arcalyst.com/files/styles/large/public/2023-04/thumbnail-arcalyst-bottle.png?itok=E_pBRjSX ARCALYST® (rilonacept) vial. https://www.arcalyst.com/sites/arcalyst.com/files/styles/retina/public/2021-03/subcutaneous_definition_desktop%403x.png?itok=RPizjIQk Self-Administered means you give the injection to yourself + Subcutaneous means under the skin https://www.arcalyst.com/sites/arcalyst.com/files/styles/retina/public/2021-03/subcutaneous_definition_mobile%403x.png?itok=5y4-K_j2 Self-Administered means you give the injection to yourself + Subcutaneous means under the skin https://www.arcalyst.com/sites/arcalyst.com/files/styles/retina/public/2021-02/dosing%402x.png?itok=jm1dbsAg ARCALYST® (rilonacept) first injection at doctor's office. https://www.arcalyst.com/sites/arcalyst.com/files/styles/retina/public/2023-03/thumbnail-how-to-use-arcalyst-guide.png?itok=gOPa-i79 ARCALYST® (rilonacept) Step-by-step instructions for self-administration brochure. https://www.arcalyst.com/sites/arcalyst.com/files/styles/icon/public/2021-02/starting_treatment%402x.png?itok=rEFnb4CZ Starting treatment. https://www.arcalyst.com/sites/default/files/styles/coh_medium/public/images/caps/testimonial-1.jpg Patient Access Lead. https://www.arcalyst.com/sites/default/files/images/caps/icon-pig.jpg Financial assistance. https://www.arcalyst.com/sites/default/files/styles/coh_medium/public/images/caps/testimonial-2.jpg Patient Access Lead. https://www.arcalyst.com/sites/arcalyst.com/files/styles/icon/public/2021-03/KOC_treatment_support%403x.png?itok=hiWN9Fda Treatment support. https://www.arcalyst.com/sites/default/files/styles/coh_medium/public/images/caps/testimonial-3.jpg Patient Access Lead. https://www.arcalyst.com/sites/arcalyst.com/files/styles/icon/public/2021-03/contact_icon%403x.png?itok=roxkKQyk Call Kiniksa OneConnect. https://www.arcalyst.com/start 2026-05-18 https://www.arcalyst.com/sites/arcalyst.com/files/styles/retina/public/2023-03/thumbnail-how-to-use-arcalyst-guide.png?itok=gOPa-i79 Step-by-step instructions for self-administration brochure. https://www.arcalyst.com/sites/arcalyst.com/files/styles/retina/public/2023-03/thumbnail-injection-tracker.png?itok=_nlvY7yh Injection Tracker. https://www.arcalyst.com/sites/arcalyst.com/files/styles/retina/public/2023-10/thumbnail-brochure-guide.png?itok=OZ2swfiE ARCALYST® patient brochure. https://www.arcalyst.com/sites/arcalyst.com/files/styles/retina/public/2023-03/thumbnail-koc-patient-brochure.png?itok=82MRRdGG Kiniksa OneConnect® Patient Support Brochure. https://www.arcalyst.com/sites/arcalyst.com/files/styles/icon/public/2021-03/contact_icon%403x.png?itok=roxkKQyk Call Kiniksa OneConnect. https://www.arcalyst.com/comenzar 2026-05-18 https://www.arcalyst.com/sites/arcalyst.com/files/styles/retina/public/2024-04/thumbnail-how-to-use-arcalyst-guide-spanish.png?itok=6t-WSgHJ Folleto con instrucciones paso a paso para la autoadministración. https://www.arcalyst.com/sites/arcalyst.com/files/styles/retina/public/2024-04/thumbnail-injection-tracker-spanish.png?itok=jE6Geq2f Seguimiento de inyección. https://www.arcalyst.com/sites/arcalyst.com/files/styles/retina/public/2025-10/thumbnail-brochure-guide-spanish.png?itok=e8RRBw15 Folleto para pacientes de ARCALYST®. https://www.arcalyst.com/sites/arcalyst.com/files/styles/retina/public/2024-04/thumbnail-koc-patient-brochure-spanish.png?itok=YYj7fJjc Folleto de soporte al paciente de Kiniksa OneConnect®. https://www.arcalyst.com/sites/arcalyst.com/files/styles/icon/public/2024-04/contact_icon%403x-spanish.png?itok=-0bdf9l9 Call Kiniksa OneConnect. https://www.arcalyst.com/recurrent-pericarditis 2026-05-18 https://www.arcalyst.com/sites/arcalyst.com/files/styles/webp_image/public/2022-12/healthy-pericardium.jpg Healthy pericardium. https://www.arcalyst.com/sites/arcalyst.com/files/styles/webp_image/public/2022-12/inflamed-pericardium.jpg Inflamed pericardium. https://www.arcalyst.com/sites/arcalyst.com/files/styles/webp_image/public/2024-03/pericarditis-one-time.png.webp?itok=HPJ4MB7z One-time episode of pericarditis heart. https://www.arcalyst.com/sites/arcalyst.com/files/styles/webp_image/public/2024-03/pericarditis-recurrent.png.webp?itok=e1eGpZKs Recurrent Pericarditis Heart. https://www.arcalyst.com/sites/arcalyst.com/files/styles/webp_image/public/2024-02/pericarditis-number.png.webp?itok=kUIPugvi ~1 in 3 people. https://www.arcalyst.com/sites/default/files/images/recurrent-pericarditis/growth_28.png 28%. https://www.arcalyst.com/sites/default/files/images/recurrent-pericarditis/growth_47.png 47%. https://www.arcalyst.com/sites/default/files/images/recurrent-pericarditis/growth_54.png 54%. https://www.arcalyst.com/sites/arcalyst.com/files/2024-04/recurrent-pericarditis-autoinflamation-cycle-desktop.png The Cycle of Autoinflammation in Recurrent Pericarditis: 1. Pericardial cell damage causes the release of IL-1α, 2. IL-1α binds to macrophages (immune cells) causing the release of IL-1β, 3.IL-1α and IL-1β bind to vascular endothelial (blood vessel) cells causing inflammation and additional cell damage, 4. Additional cell damage causes the cycle of autoinflammation to continue. https://www.arcalyst.com/sites/arcalyst.com/files/2024-02/banner-zenda-mobile.jpg Zenda. https://www.arcalyst.com/sites/arcalyst.com/files/styles/webp_image/public/2024-02/doctor-dicussion-guide.png.webp?itok=Tpr20B7e Starting a conversation with your doctor about recurrent pericarditis and treatment brochure. https://www.arcalyst.com/sites/arcalyst.com/files/styles/webp_image/public/2024-02/arcalyst-injection-bottle.png.webp?itok=SEtSyDq1 ARCALYST® injection vial. https://www.arcalyst.com/sites/default/files/images/recurrent-pericarditis/Peri-cardio-itis_desktop.jpg PERI+CARD(IO)+ITIS. https://www.arcalyst.com/sites/default/files/images/recurrent-pericarditis/testimonial_3_desktop.jpg Person with one hand on their chest. https://www.arcalyst.com/sites/default/files/styles/coh_large/public/images/recurrent-pericarditis/Auto%2Binflammation.jpg Auto+inflammation. https://www.arcalyst.com/sites/default/files/styles/coh_medium/public/images/recurrent-pericarditis/Yvette%20thumbnail.jpg Yvette. https://www.arcalyst.com/take-control 2026-05-18 https://www.arcalyst.com/sites/arcalyst.com/files/2024-02/banner-warren-mobile.jpg Warren. https://www.arcalyst.com/sites/arcalyst.com/files/2024-04/take-control-autoinflamation-cycle-desktop.png The Cycle of Autoinflammation in Recurrent Pericarditis: 1. Pericardial cell damage causes the release of IL-1α, 2. IL-1α binds to macrophages (immune cells) causing the release of IL-1β, 3.IL-1α and IL-1β bind to vascular endothelial (blood vessel) cells causing inflammation and additional cell damage, 4. Additional cell damage causes the cycle of autoinflammation to continue. https://www.arcalyst.com/sites/arcalyst.com/files/styles/webp_image/public/2025-06/take-control_side-effects.png.webp?itok=AbIF5hJW Patient at a doctor's office talking to a doctor. https://www.arcalyst.com/sites/default/files/images/take-control/study_table_desktop.jpg 1. Time to monotherapy, reduced pain and inflammation evaluated in 86 patients. 2. Risk of recurrence evaluated in 61 patients. 3. Long-term safety and efficacy evaluated in 74 patients. https://www.arcalyst.com/sites/default/files/images/take-control/headphone_icon.jpg Call Kiniksa Pharmaceuticals. https://www.arcalyst.com/how-to-use-arcalyst 2026-05-18 https://www.arcalyst.com/sites/default/files/styles/coh_medium/public/images/how-to-use-arcalyst/Arcalyst-Vial.jpg ARCALYST® injection vial. https://www.arcalyst.com/sites/arcalyst.com/files/styles/webp_image/public/2023-03/thumbnail-how-to-use-arcalyst-guide.png.webp?itok=jTBfGrx8 ARCALYST® (rilonacept) Step-by-step instructions for self-administration brochure. https://www.arcalyst.com/sites/default/files/images/how-to-use-arcalyst/testimonial_cathy_desktop.jpg Cathy. https://www.arcalyst.com/sites/default/files/images/how-to-use-arcalyst/speaker_icon.jpg Connect with Kiniksa OneConnectTM team. https://www.arcalyst.com/sites/default/files/images/how-to-use-arcalyst/loading-dose-table-desktop.png Adults: loading dose of 320mg with a weekly maintenance dose of 160mg. Adolescents: loading dose of 4.4mg/kg with a weekly maintenance dose of 2.2mg/kg. https://www.arcalyst.com/kiniksa-oneconnect-support 2026-05-18 https://www.arcalyst.com/sites/default/files/styles/coh_large/public/styles/coh_large/public/images/kiniksa-oneconnect/17366_Kiniksa_OneConnect-R_Logo_RGB.jpg Kiniksa OneConnect® logo. https://www.arcalyst.com/sites/arcalyst.com/files/2024-02/kiniksa-oneconnect-banner-mobile.jpg Warren. https://www.arcalyst.com/sites/default/files/styles/coh_medium/public/styles/coh_large/public/images/resources/Shania.jpg Patient Access Lead. https://www.arcalyst.com/sites/default/files/styles/coh_medium/public/styles/coh_large/public/images/resources/Ada.jpg Patient Access Lead. https://www.arcalyst.com/sites/default/files/styles/coh_large_landscape/public/styles/coh_large/public/images/kiniksa-oneconnect/Hannah.jpg Patient Access Lead. https://www.arcalyst.com/sites/default/files/styles/coh_medium/public/styles/coh_large/public/images/kiniksa-oneconnect/Bibiana.jpg Patient Access Lead. https://www.arcalyst.com/sites/default/files/styles/coh_medium/public/images/kiniksa-oneconnect/low-cost.jpg Low out-of-pocket cost $0. https://www.arcalyst.com/phone.png Call Kiniksa OneConnect. https://www.arcalyst.com/personal-stories 2026-05-18 https://www.arcalyst.com/sites/arcalyst.com/files/styles/webp_image/public/2024-03/dr-ryan.png.webp?itok=iORi_3tU Dr. Ryan sitting at a desk. https://www.arcalyst.com/sites/arcalyst.com/files/styles/webp_image/public/2024-03/zenda-checking-in-while-taking-arcalyst.png.webp?itok=FfY5E4QK Zenda and Dr. Ryan checking in. https://www.arcalyst.com/sites/arcalyst.com/files/styles/webp_image/public/2024-03/zenda-tips-talking-to-your-doctor_0.png.webp?itok=-evYHuQp Zenda and Dr. Ryan talking. https://www.arcalyst.com/sites/arcalyst.com/files/styles/webp_image/public/2024-03/thumb-caregivers-perspective-1.png.webp?itok=MeUP7zpy Ken and Cathy reading. https://www.arcalyst.com/sites/arcalyst.com/files/styles/webp_image/public/2024-03/thumb-caregivers-perspective-2.png.webp?itok=4xiQpGNw Ken and Cathy walking. https://www.arcalyst.com/sites/arcalyst.com/files/styles/webp_image/public/2024-03/A%20Caregiver%E2%80%99s%20Perspective%20Fran%2C%20wife%20of%20Warren%20Burden%20of%20RP.png.webp?itok=cQNktvUp Fran and Warren walking. https://www.arcalyst.com/sites/default/files/styles/coh_medium/public/images/personal-stories/video-thumbnail-1_0.jpg Warren. https://www.arcalyst.com/sites/default/files/styles/coh_medium/public/images/personal-stories/video-thumbnail-2_0.jpg Cathy. https://www.arcalyst.com/sites/default/files/styles/coh_medium/public/images/personal-stories/video-thumbnail-3.jpg Zenda. https://www.arcalyst.com/sites/default/files/styles/coh_medium/public/images/personal-stories/warren-profile-card.jpg Warren standing. https://www.arcalyst.com/zenda-standing.jpg Zenda standing. https://www.arcalyst.com/cathy-standing.jpg Cathy standing. https://www.arcalyst.com/resources 2026-05-18 https://www.arcalyst.com/sites/arcalyst.com/files/styles/webp_image/public/2024-03/icon-pericarditis-alliance_0.png.webp?itok=Yf_XJ7r9 Pericarditis Alliance logo. https://www.arcalyst.com/sites/arcalyst.com/files/styles/webp_image/public/2024-03/icon-myocarditis-foundation.png.webp?itok=RzuofEJ- Myocarditis Foundation logo. https://www.arcalyst.com/sites/arcalyst.com/files/styles/webp_image/public/2024-03/icon-nord.png.webp?itok=px9mGigB NORD logo. https://www.arcalyst.com/sites/default/files/styles/coh_medium/public/images/resources/res-1.jpg ARCALYST® (rilonacept) brochure. https://www.arcalyst.com/sites/default/files/styles/coh_medium/public/images/resources/res-2.jpg Starting A Conversation - a guide to talking to your doctor about recurrent pericarditis and treatment. https://www.arcalyst.com/sites/default/files/styles/coh_medium/public/images/resources/res-3.jpg ARCALYST® (rilonacept) step-by-step instructions for self-administration brochure. https://www.arcalyst.com/sites/default/files/styles/coh_medium/public/images/resources/injection-video-thumbnail%201.jpg ARCALYST® (rilonacept) vial. https://www.arcalyst.com/sites/default/files/styles/coh_medium/public/images/resources/res-5.jpg Keep a record of your treatment - ARCALYST® (rilonacept) injection tracker manual. https://www.arcalyst.com/sites/default/files/images/resources/testimonial-card-cathy_desktop%201.jpg Cathy. https://www.arcalyst.com/sites/default/files/styles/coh_medium/public/styles/coh_large/public/images/resources/Onconnect%20video%20thumbnail.jpg Welcome to the Kiniksa OneConnectTM Patient Support Program. https://www.arcalyst.com/sites/default/files/styles/coh_medium/public/styles/coh_large/public/images/resources/traveling-treatment-thumbnail.jpg Traveling while on treatment medication guide. https://www.arcalyst.com/sites/default/files/styles/coh_medium/public/styles/coh_large/public/images/resources/treatment-routine-thumbnail.jpg Creating a treatment routine brochure. https://www.arcalyst.com/sites/default/files/styles/coh_medium/public/styles/coh_large/public/images/resources/handle-your-medication.jpg How to store and handle your medication brochure. https://www.arcalyst.com/sites/default/files/styles/coh_medium/public/styles/coh_large/public/images/resources/Oneconnect%20Thumbnail.jpg Welcome to the Kiniksa OneConnect® Patient Support Program. https://www.arcalyst.com/tv-commercial 2026-05-18 https://www.arcalyst.com/webinars 2026-05-18 https://www.arcalyst.com/sites/arcalyst.com/files/styles/webp_image/public/2024-01/zenda-speaker-thumbnail.png.webp?itok=JkwZIugH Thumbnail of Zenda. https://www.arcalyst.com/sites/arcalyst.com/files/styles/webp_image/public/2023-10/Janice-thumbnail.png.webp?itok=oBFWm-8a Thumbnail of Janice. https://www.arcalyst.com/sites/arcalyst.com/files/styles/webp_image/public/2024-01/david-homan-speaker-thumbnail.png.webp?itok=ihiIPyLF Thumbnail of Dr. Homan. https://www.arcalyst.com/sites/arcalyst.com/files/styles/webp_image/public/2023-12/thumbnail-yvette.jpg.webp?itok=QuDU1NmG Thumbnail of Yvette. https://www.arcalyst.com/sites/arcalyst.com/files/styles/webp_image/public/2023-12/thumbnail-andrew-ertel.jpg.webp?itok=44rSBOSE Thumbnail of Dr. Ertel. https://www.arcalyst.com/sites/arcalyst.com/files/styles/webp_image/public/2023-10/cathy-thumbnail.png.webp?itok=gS3tVmT_ Thumbnail of Cathy. https://www.arcalyst.com/sites/arcalyst.com/files/styles/webp_image/public/2023-10/john-isaac-thumbnail.png.webp?itok=3Coe6DYI Thumbnail of Dr. Isaac. https://www.arcalyst.com/sites/arcalyst.com/files/styles/webp_image/public/2023-02/jennifer-cronin.png.webp?itok=ODfIdyRB Thumbnail of Jennifer. https://www.arcalyst.com/sites/arcalyst.com/files/styles/webp_image/public/2023-04/thumb-gary.png.webp?itok=Rr95KbDZ Thumbnail of Gary. https://www.arcalyst.com/sites/arcalyst.com/files/styles/webp_image/public/2023-04/thumb-john-ryan.png.webp?itok=bsiq9tbh Thumbnail of Dr. Ryan. https://www.arcalyst.com/sites/arcalyst.com/files/styles/webp_image/public/2024-02/thumb-dan-yi.png.webp?itok=58an4GDt Thumbnail of Dan. https://www.arcalyst.com/sites/arcalyst.com/files/styles/webp_image/public/2022-11/thumb-dr-norman.png.webp?itok=Wro_KhBt Thumbnail of Dr. Lepor. https://www.arcalyst.com/sites/arcalyst.com/files/styles/webp_image/public/2022-11/vanessa_0.png.webp?itok=v-ILkYSz Thumbnail of Vanessa. https://www.arcalyst.com/sites/arcalyst.com/files/styles/webp_image/public/2023-02/cara-headshot.png.webp?itok=LxMnHurP Thumbnail of Cara. https://www.arcalyst.com/sites/arcalyst.com/files/styles/webp_image/public/2023-02/yvette.png.webp?itok=cVe_FuH8 Thumbnail of Yvette. https://www.arcalyst.com/sites/arcalyst.com/files/styles/webp_image/public/2022-10/martin-lewinter.png.webp?itok=H7XoO1CX Thumbnail of Dr. LeWinter. https://www.arcalyst.com/sites/arcalyst.com/files/styles/webp_image/public/2022-10/cathy-m.png.webp?itok=jDoCe60w Thumbnail of Cathy. https://www.arcalyst.com/sites/arcalyst.com/files/styles/webp_image/public/2022-10/john-paolini.png.webp?itok=zWYNHJxG Thumbnail of Dr. Paolini.